EVOLUTION × GENETICS × LIFE

The Cell That Swallowed a Bacterium

~1.9 billion years ago (order of events debated)

Proterozoic · Paleoproterozoic · Orosirian

A bacterium ended up inside another cell, and stayed. Over generations it handed most of its genome to its host's nucleus, kept a small chromosome of its own, and became the mitochondrion, the organelle in which complex cells burn oxygen. The host was an archaeon; the lodger an alphaproteobacterium, or a bacterium from a lineage that split off just before that group.

Why it matters

One cell entering another, just once, is the reason there are organisms large enough to see.

Dating & uncertaintyDisputed

The merger itself leaves no fossil. Phylogenomics reads it in the branch lengths of the proteins it brought, and disagrees on the order of events: whether mitochondria entered a simple host and drove the rest, or joined a cell that was already complex.

Sources

  1. Roger et al. (2017), Current Biology · The origin and diversification of mitochondria
  2. Pittis & Gabaldón (2016), Nature · Late acquisition of mitochondria by a host with chimeric prokaryotic ancestry
  3. Martijn et al. (2018), Nature · Deep mitochondrial origin outside the sampled alphaproteobacteria

Earth history as one day

13:57:2110 h 3 min before midnight

if Earth’s 4.54 billion years were compressed into a single day

See it on the timeline

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